Description
Product Characteristics: AC133 antibody, Antigen AC133 antibody, CD133 antibody, CORD12 antibody, Hematopoietic stem cell antigen antibody, hProminin antibody, MCDR2 antibody, MSTP061 antibody, OTTHUMP00000217744 antibody, OTTHUMP00000217745 antibody, OTTHUMP00000217746 antibody, PROM1 antibody, PROM1_HUMAN antibody, Prominin I antibody, Prominin like 1 antibody, Prominin like protein 1 precursor antibody, Prominin mouse like 1 antibody, Prominin-1 antibody, Prominin-like protein 1 antibody, Prominin1 antibody, PROML1 antibody, RP41 antibody, STGD4 antibody
Target Information: This gene encodes a pentaspan transmembrane glycoprotein. The protein localizes to membrane protrusions and is often expressed on adult stem cells, where it is thought to function in maintaining stem cell properties by suppressing differentiation. Mutations in this gene have been shown to result in retinitis pigmentosa and Stargardt disease. Expression of this gene is also associated with several types of cancer. This gene is expressed from at least five alternative promoters that are expressed in a tissue-dependent manner. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]